Genetic Mutations: A Short Guide (Free Notes Included)


Genetic Mutations
A General Illustration of Mutation

You may have heard the phrase "genetic mutations" quite often in genetics, but what does it actually imply? We shall dig into the interesting topic of genetic mutations in this article, illuminating their importance, sorts, and probable repercussions.

The Basics of Genetic Mutations

Genetic mutations are alterations to the DNA sequence that can impact an organism's traits or attributes. These mutations can occur naturally or as a result of external stimuli like as radiation, poisons, or even errors in DNA replication.

Types of Genetic Mutations

1. Point Mutations

A point mutation mainly occurs as one nucleotide in a DNA sequence is substituted by another. Point mutations are further subdivided as follows:

Missense Mutations

Missense mutations involve the replacement of one amino acid for another, potentially impacting the function of the protein.

Nonsense Mutations

A premature stop codon is introduced by nonsense mutations, which results in the synthesis of an ineffective protein.

2. Frameshift Mutations

A premature stop codon is introduced by nonsense mutations, which results in the synthesis of an ineffective protein.

3. Structural Mutations

Structural mutations occur when the overall structure of a chromosome is altered, such as duplications, deletions, or inversions. These changes may result in genetic disorders.

Importance of Genetic Mutations

Genetic mutation is the primary source that results in diversity on the planet. They alter populations that may either be beneficial, insignificant, or even adverse, thereby driving evolution.

Human Genetic Mutations

Genetic alterations may have various effects on a person's health. Indeed certain mutations may increase risk of specific diseases, others may be linked to inherited genetic issues. Knowing a person's genetic composition may be immensely valuable in personalised therapy and sickness prevention.

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